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for instance, its easier to skip the gym or eat the familiar comfort food (and now one might justify it by Im on a weight-loss shot anyway)

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Just make sure you dont overdo it and burn too many calories

For non-diabetics taking GLP agonists for other reasons most likely reducing body weight the results of this study may not be applicable as the interaction of diabetes-related inflammation, and such may be the reason for such wide-ranging GLP agonist effects. The study authors conclude that their results provide insights into the benefits and risks of GLP-1R and may be useful for informing clinical care and guiding research agendas